Edward Crane may refer to:
Ed Crane (political activist) (born 1944), founder of the Cato Institute
Ed Crane (journalist), reporter for CBS News
Ed Crane (baseball) (1862–1896), American right-handed pitcher and outfielder in Major League Baseball
Edward Crane (mayor), mayor of Cambridge, Massachusetts
Ed Crane, the lead character of the 2001 film The Man Who Wasn’t There
Eddie Crane, fictional canine character on sitcom Frasier
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